The following articles (labelled with PubMed ID or TBD) are for your review| PMID | Article Title | Published | Deposition |
|---|
| 34800875 |
Macrocyclic BACE1 inhibitors with hydrophobic cross-linked structures: Optimization of ring size and ring structure. |
15-DEC-2021 |
07-MAR-2023 |
| 34700240 |
Structure-activity relationship study of hydroxyethylamine isostere and P1' site structure of peptide mimetic BACE1 inhibitors. |
15-NOV-2021 |
24-AUG-2022 |
| 23910984 |
Adipogenetic effects of retrofractamide A derivatives in 3T3-L1 cells. |
01-SEP-2013 |
01-SEP-2020 |
| 12128170 |
Effects of 12 Ca2+ antagonists on multidrug resistance, MDR1-mediated transport and MDR1 mRNA expression. |
XX-AUG-2002 |
30-AUG-2020 |
| 21392990 |
Design and synthesis of several small-size HTLV-I protease inhibitors with different hydrophilicity profiles. |
15-APR-2011 |
29-AUG-2020 |
| 22014094 |
Structure-based design, synthesis, and evaluation of peptide-mimetic SARS 3CL protease inhibitors. |
08-DEC-2011 |
29-AUG-2020 |
| 21316958 |
Maintaining potent HTLV-I protease inhibition without the P3-cap moiety in small tetrapeptidic inhibitors. |
15-MAR-2011 |
28-AUG-2020 |
| 19954246 |
Small-sized human immunodeficiency virus type-1 protease inhibitors containing allophenylnorstatine to explore the S2' pocket. |
10-DEC-2009 |
27-AUG-2020 |
| 19362479 |
New developments for the design, synthesis and biological evaluation of potent SARS-CoV 3CL(pro) inhibitors. |
15-MAY-2009 |
27-AUG-2020 |
| 18426195 |
Combination of non-natural D-amino acid derivatives and allophenylnorstatine-dimethylthioproline scaffold in HIV protease inhibitors have high efficacy in mutant HIV. |
22-MAY-2008 |
26-AUG-2020 |
| 18558491 |
Locking the two ends of tetrapeptidic HTLV-I protease inhibitors inside the enzyme. |
15-JUL-2008 |
26-AUG-2020 |
| 26264846 |
Evaluation of transition-state mimics in a superior BACE1 cleavage sequence as peptide-mimetic BACE1 inhibitors. |
31-AUG-2015 |
17-NOV-2016 |
| 25987378 |
Inhibitors of melanogenesis in B16 melanoma 4A5 cells from flower buds of Lawsonia inermis (Henna). |
04-JUN-2015 |
15-OCT-2016 |
| 24631188 |
Optimization of plasmepsin inhibitor by focusing on similar structural feature with chloroquine to avoid drug-resistant mechanism of Plasmodium falciparum. |
31-MAR-2014 |
06-FEB-2015 |
| 23993670 |
Novel BACE1 inhibitors with a non-acidic heterocycle at the P1' position. |
07-OCT-2013 |
13-APR-2014 |
| 23375227 |
Critical role of a methyl group on the¿-lactone ring of annonaceous acetogenins in the potent inhibition of mitochondrial complex I. |
15-FEB-2013 |
24-SEP-2013 |
| 14510595 |
Structures of new friedelane-type triterpenes and eudesmane-type sesquiterpene and aldose reductase inhibitors from Salacia chinensis. |
26-SEP-2003 |
16-DEC-2012 |
| 18249539 |
BACE1 inhibitors: optimization by replacing the P1' residue with non-acidic moiety. |
10-MAR-2008 |
15-DEC-2012 |
| 18006315 |
Truncation and non-natural amino acid substitution studies on HTLV-I protease hexapeptidic inhibitors. |
09-JAN-2008 |
14-DEC-2012 |
| 15501070 |
Identification of peptidomimetic HTLV-I protease inhibitors containing hydroxymethylcarbonyl (HMC) isostere as the transition-state mimic. |
25-OCT-2004 |
01-DEC-2012 |
| 11549448 |
Design and synthesis of new inhibitors of HIV-1 protease dimerization with conformationally constrained templates. |
10-SEP-2001 |
04-OCT-2012 |
| 11459643 |
Phytoestrogens from the roots of Polygonum cuspidatum (Polygonaceae): structure-requirement of hydroxyanthraquinones for estrogenic activity. |
18-JUL-2001 |
03-OCT-2012 |
| 21803585 |
Structure-guided design and synthesis of P1' position 1-phenylcycloalkylamine-derived pentapeptidic BACE1 inhibitors. |
22-AUG-2011 |
23-MAR-2012 |
| 21493073 |
Structural requirements of flavonoids for the adipogenesis of 3T3-L1 cells. |
28-APR-2011 |
04-DEC-2011 |
| 20634066 |
Improvement of both plasmepsin inhibitory activity and antimalarial activity by 2-aminoethylamino substitution. |
27-JUL-2010 |
19-MAR-2011 |
| 20381362 |
Design of pentapeptidic BACE1 inhibitors with carboxylic acid bioisosteres at P1' and P4 positions. |
30-APR-2010 |
19-NOV-2010 |
| 20189399 |
Melanogenesis inhibitors from the desert plant Anastatica hierochuntica in B16 melanoma cells. |
10-MAR-2010 |
02-SEP-2010 |
| 19615910 |
Melanogenesis inhibitors from the rhizomes of Alpinia officinarum in B16 melanoma cells. |
11-AUG-2009 |
31-AUG-2010 |
| 18400502 |
Synthesis and activity of tetrapeptidic HTLV-I protease inhibitors possessing different P3-cap moieties. |
26-MAY-2008 |
11-JAN-2010 |
| 19345096 |
Significance of interactions of BACE1-Arg235 with its ligands and design of BACE1 inhibitors with P2 pyridine scaffold. |
17-APR-2009 |
11-JAN-2010 |
| 18952439 |
Antimalarial activity enhancement in hydroxymethylcarbonyl (HMC) isostere-based dipeptidomimetics targeting malarial aspartic protease plasmepsin. |
17-NOV-2008 |
11-JAN-2010 |
| 18477507 |
Effects of amide constituents from pepper on adipogenesis in 3T3-L1 cells. |
30-MAY-2008 |
11-JAN-2010 |
| 12193020 |
New flavonol oligoglycosides and polyacylated sucroses with inhibitory effects on aldose reductase and platelet aggregation from the flowers of Prunus mume. |
23-AUG-2002 |
11-JAN-2010 |
| 18261904 |
Novel non-peptidic and small-sized BACE1 inhibitors. |
10-MAR-2008 |
11-NOV-2009 |
| 10866387 |
'Double-Drugs'--a new class of prodrug form of an HIV protease inhibitor conjugated with a reverse transcriptase inhibitor by a spontaneously cleavable linker. |
07-NOV-2000 |
10-NOV-2009 |
| 12467624 |
Design and synthesis of pseudo-symmetric HIV protease inhibitors containing a novel hydroxymethylcarbonyl (HMC)-hydrazide isostere. |
06-DEC-2002 |
10-NOV-2009 |
| 14643307 |
KMI-008, a novel beta-secretase inhibitor containing a hydroxymethylcarbonyl isostere as a transition-state mimic: design and synthesis of substrate-based octapeptides. |
03-DEC-2003 |
10-NOV-2009 |
| 15006396 |
KMI-358 and KMI-370, highly potent and small-sized BACE1 inhibitors containing phenylnorstatine. |
09-MAR-2004 |
10-NOV-2009 |
| 15582441 |
Design and synthesis of highly active Alzheimer's beta-secretase (BACE1) inhibitors, KMI-420 and KMI-429, with enhanced chemical stability. |
07-DEC-2004 |
10-NOV-2009 |
| 16757166 |
beta-Secretase inhibitors: modification at the P4 position and improvement of inhibitory activity in cultured cells. |
17-JUL-2006 |
10-NOV-2009 |
| 16481167 |
Design and synthesis of potent beta-secretase (BACE1) inhibitors with P1' carboxylic acid bioisosteres. |
20-MAR-2006 |
10-NOV-2009 |
| 17400453 |
Additional interaction of allophenylnorstatine-containing tripeptidomimetics with malarial aspartic protease plasmepsin II. |
14-MAY-2007 |
10-NOV-2009 |
| 10206539 |
A new class of anti-HIV agents: synthesis and activity of conjugates of HIV protease inhibitors with a reverse transcriptase inhibitor. |
22-JUN-1999 |
10-NOV-2009 |
| 10698435 |
Structure-activity relationship studies of chloromethyl ketone derivatives for selective human chymase inhibitors. |
28-MAR-2000 |
10-NOV-2009 |
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